Laredo to Guadalajara / Chapala / Vallarta. Very popular route. Driving is easy, suitable for RV's, cars, bikes.
There are two routes to Guadalajara. This is more commonly used. I think it is less confusing route through Zacatecas. But RV Caravans use the Zacatecas / Aguascalientes route. I am transcribing my notes on that one, but I personally think this is better for you.
Pet-friendly hotels, RV parks and wonderful side-trips that are just off the main road are included to use (or not). Map of new Macrolibramiento & directions to RV park included.