San Miguel de Allende is in the colonial historic center of Mexico. This is considered a "safe" route and destination by those who worry about safety in Mexico. My roadlog and detailed maps will guide you from the Columbia Bridge near Laredo, TX to San Miguel de Allende via the most direct toll route.
In itself, San Miguel is a fascinating town, a Magical Town, full of culture and art and history. Using San Miguel as a home base, you could branch out and discover the "real" Mexico missed by those who just fly over. Guanajuato, for instance, is only an hour away. It is considered the most European of Mexico's cities. Very cultured.
Gas stations, safe roadside eateries, hotels take care of those who just want to get there. For those who want to experience Mexico on the way, it includes interesting towns only a few miles off the toll road. They include: a ghost town, healing hot springs, rebozo factories.